- The title is a reference to the 1921 F. Scott Fitzgerald short story The Curious Case of Benjamin Button, which would later become a hit 2008 film of the same name starring Brad Pritt.
- The end of act one is a parody of Lost.
- Rallo's speech at the C.H.O.D.E. benefit makes references to The Lion King, Hotel Rwanda, Coming to America, and Out of Africa.
- When Cleveland and his friends are thrown out of the Stool, they run in midair, parodying the Scooby-Doo cartoons.
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